Melarsoprol–cyclodextrins inclusion complexes
نویسندگان
چکیده
منابع مشابه
Melarsoprol-cyclodextrins inclusion complexes.
Melarsoprol, a water-insoluble drug, is mainly used in the treatment of trypanosomiasis and has demonstrated an in vitro activity on myeloid and lymphoid leukemia derived cell lines. It is marketed as a very poorly tolerated non-aqueous solution (Arsobal). The aim of our work was to develop melarsoprol-cyclodextrin complexes in order to improve the tolerability and the bioavailability of melars...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2005
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2005.09.003